EARLY LIFE ADVERSITY PREDICTS BRAIN-GUT ALTERATIONS ASSOCIATED WITH INCREASED STRESS AND MOOD

Alterations in the brain-gut system have been implicated in various disease states, but little is known about how early-life adversity (ELA) impacts development and adult health as mediated by brain-gut interactions.We hypothesize that ELA disrupts components of the brain-gut system, thereby increasing susceptibility to disordered mood.In a sample

Keratinocytes of the mammalian skin provide not only mechanical protection for Needs Audit the tissues, but also transmit mechanical, chemical, and thermal stimuli from the external environment to the sensory nerve terminals.Sensory nerve fibers penetrate the epidermal basement membrane and function in the tight intercellular space among keratinocy